Enflurane으로 인하여 발생한 마취 중 급성과민증
Intraoperative Anaphylatic Reaction to Enflurane -A Case Report -
박창주, 서광석, 김현정, 최진영, 염광원,
소속 상세정보
박창주 ( Park Chang-Joo ) - 서울대학교 치과대학 치과마취과학교실
서광석 ( Seo Kwang-Suk ) - 서울대학교 치과병원 마취통증의학과
김현정 ( Kim Hyun-Jeong ) - 서울대학교 치과대학 치과마취과학교실
최진영 ( Choi Jin-Young ) - 서울대학교 치과대학 구강악안면외과학교실
염광원 ( Yeom Kwang-Won ) - 서울대학교 치과대학 치과마취과학교실
KMID : 0980220040040010025
Abstract
Anaphylactic reactions to anesthetic drugs could potentially produce life-threatening immune-mediated crisis. Most published reports are associated with neuromuscular blockers and anaphylactic reactions to inhalation anesthetics are rare. A 25-year-old male patient with no significant medical history and no previous abnormal drug reaction was scheduled for orthognathic surgery under general anesthesia. After uneventful anesthetic induction and nasotracheal intubation, generalized urticaria and erythema were detected during the maintenance period with O_2-N_2O-enflurane. No severe changes of vital signs and no ventilation problem were accompanied. The operation was cancelled and the cutaneous lesions were faded away during the recovery with 100% O_2. The skin-prick and intradermal tests showed that he was hypersensitive to all halogenated inhalation anesthetics including enflurane and not to intravenous anesthetics and neuromuscular blockers. The re-operation was safely carried out under intravenous anesthesia with propofol-fentanyl-vecuronium. We report this case of intraoperative anaphylactic reaction to enflurane with literature review.
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